FAQ

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Please register for this website first, registration is free, please put in an identifiable nickname and your real name, your real name will not be shown publically. When registering please provide your address, we may need to send information or even free stuff. Please remember when registering for the website to fill you address and contact details in your account.

Once you have registered, you can then proceed to the medical form section on this website, this will send the form to us, no information will be shared with anyone outside this site. The medical form which when filled in will provide us with your current condition(s). If you are filling the form out while with the medical user please put your name in as the helper name.

Once you have sent the medical form out please contact us, you can phone Dark city on 0161 298 0298, we can call you back after you contact us, so the phone call does not cost you anything.

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Before the 1980s, it was often speculated that cannabinoids produced their physiological and behavioral effects via nonspecific interaction with cell membranes, instead of interacting with specific membrane-bound receptors. The discovery of the first cannabinoid receptors in the 1980s helped to resolve this debate. At present, there are two known types of cannabinoid receptors, termed CB1 and CB2 with mounting evidence of more. The human brain has more cannabinoid receptors than any other G protein-coupled receptor type.

Cannabinoid receptor type 1

CB₁ receptors are found primarily in the brain, more specifically in the basal ganglia and in the limbic system, including the hippocampus and the striatum. They are also found in the cerebellum and in both male and female reproductive systems. CB₁ receptors are absent in the medulla oblongata, the part of the brain stem responsible for respiratory and cardiovascular functions. CB1 is also found in the human anterior eye and retina.

Cannabinoid receptor type 2

CB2 receptors are predominantly found in the immune system, or immune-derived cells with the greatest density in the spleen. While found only in the peripheral nervous system, a report does indicate that CB2 is expressed by a subpopulation of microglia in the human cerebellum. CB2 receptors appear to be responsible for the anti-inflammatory and possibly other therapeutic effects of cannabis seen in animals.

https://en.wikipedia.org/wiki/Cannabinoid

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A cannabinoid is one of a class of diverse chemical compounds that acts on cannabinoid receptors in cells.

The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC), the primary psychoactive compound in cannabis. Cannabidiol (CBD) is another major constituent of the plant. There are at least 113 different cannabinoids isolated from cannabis, exhibiting varied effects. Here are some examples.

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With testing of extracts you can see from the test results the percentages of different cannabinoids contained. Some extracts are more suitable for different circumstances or people. Without testing your extract you will not know how to dose yourself accurately. The results of the test also give you a guide to the quality of your extract.

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Decarboxylation is a chemical reaction that removes a carboxyl group and releases carbon dioxide (CO₂). Usually, decarboxylation refers to a reaction of carboxylic acids, removing a carbon atom from a carbon chain. Examples would be converting THCA to THC, CBDA to CBD.

Some uses of the acid form (THCA) are more suited conditions and the decarboxylated cannabinoids are suited to other conditions.

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Winterized oil is full extract cannabis oil (FECO) that has been through a process that removes waxes. The result is that you will have a much cleaner extract and generally higher cannabinoid content. Winterized oil can be used in making tinctures and epen liquid as it has no waxes to clog filers in epens, and is easier to blend into a carrier medium.

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FECO is an abbreviation for "full extract cannabis oil" this may also be called full spectrum, meaning that the extraction contains all cannabinoids that have been extracted from the plant material. Some full extracts are taken from from the whole plant. Some extracts are taken from the flowers only, generally these have a higher cannabinoid content. None of the cannabinoids have been taken from the extraction and are not made from combined isolated cannabinoids.